Medical Tourism Blog
Effective Juvelook Volume Filler for Lip Wrinkles Treatment in Korea

Table of contents
- Juvelook Volume Filler: A Detailed Medical Overview
- Best Clinics in Korea for Lip Wrinkles
- The Juvelook Volume Filler Procedure in South Korea: A Step-by-Step Guide
- Cost Analysis: Juvelook Volume Filler for Medical Tourists
- Patient Experiences and Expected Outcomes for Lip Wrinkles
- Conclusion: Making an Informed Decision for Your Skin Health
- References
Considering treatment in Korea? Everything you need to know e.g. — how to avoid scams, visas, interpreters, recovery tips — in our Medical Tourism Master Guide. Plan with confidence in minutes, not weeks!
What are Lip Wrinkles?
Lip wrinkles, often called "fine radial lines on lips," are vertical creases that show up around the mouth—especially above the upper lip, sometimes stretching toward the nose. These lines can be faint or deep, and they often become more obvious when lipstick settles into them.
Common Pseudonyms: "Smoker's Lines," "Lipstick Lines," and "Perioral Rhytides"
You might hear lip wrinkles referred to as "smoker's lines" or "lipstick lines," highlighting either their cause or how makeup can accentuate them. Clinically, they're known as "perioral rhytides" or "perioral wrinkles," with "peri-" meaning "around" and "oral" referring to the mouth. While smoking is a well-known cause, these lines can develop in anyone due to aging and other factors, so non-smokers shouldn't feel singled out.
Causes and Contributing Factors
Lip wrinkles develop for several reasons:
- Aging: As we age, our skin produces less collagen and elastin, leading to less elasticity and more wrinkles.
- Muscle Activity: The orbicularis orris muscle, which helps us pucker our lips, gets more active over time. Repetitive movements like sipping through a straw or certain facial expressions can deepen these lines.
- Environmental Factors: Sun exposure is a big culprit—UV rays break down collagen, especially in the thin skin around the lips.
- Smoking: Beyond the repetitive motion, chemicals in cigarettes damage collagen and blood flow, speeding up wrinkle formation.
- Lifestyle and Genetics: Excessive alcohol, lack of sleep, genetics (like fair skin or thin lips), and even frequent waxing can all play a role.
Severity and Related Concerns
Lip wrinkles are usually classified as mild (shallow), moderate (deeper), or severe (thick, pronounced). They can make someone look older or give the impression of an unhealthy lifestyle, especially when called "smoker's lines." Over time, these wrinkles can also make lips look smaller or less defined.
Juvelook Volume Filler: A Detailed Medical Overview
What is Juvelook Volume Filler?
Juvelook is a new type of injectable for skin rejuvenation, known as a "hybrid filler" or "hybrid biostimulator." It combines poly-D,L-lactic acid (PDLLA) microparticles and hyaluronic acid (HA). "Juvelook Volume" (also called Lenisna) contains a higher concentration of these ingredients—200mg of PDLLA with HA—making it ideal for deeper wrinkles and volume loss, especially around the lips.
How Juvelook Volume Filler Works: Dual-Action Mechanism

Juvelook Volume Filler works in two phases:
- Immediate Effect: The hyaluronic acid (HA) hydrates and plumps the skin right away, smoothing fine lines and helping the PDLLA particles stay in place.
- Long-Term Effect: The PDLLA microparticles stimulate your body to produce more collagen over several months, improving skin firmness, elasticity, and texture. These particles are biodegradable and break down naturally over 1–2 years. Juvelook's patented spherical PDLLA particles are designed to minimize irritation and lumps.
Key Benefits and Applications for Skin Rejuvenation
Juvelook Volume Filler offers several benefits:
- Wrinkle Reduction: Smooths fine lines and wrinkles, including perioral rhytides ("smoker's lines"), crow's feet, and nasolabial folds.
- Improved Elasticity and Firmness: Boosts collagen for firmer, more elastic skin.
- Natural Volume Restoration: Restores lost volume for a youthful look without appearing overfilled.
- Enhanced Texture and Radiance: Improves skin tone and texture for a radiant complexion.
- Pore Minimization: Reduces the appearance of enlarged pores.
- Acne Scar Improvement: Helps repair pitted scars by stimulating collagen.
- Under-Eye Rejuvenation: Fills hollow areas and reduces dark circles.
- Minimal Downtime: Most people recover quickly and can resume daily activities soon after.
Safety Profile, Potential Side Effects, and Important Contraindications
Juvelook Volume Filler is considered safe, thanks to its biocompatible ingredients (PDLLA and HA) and regulatory approvals from the FDA, KFDA, and CE. Common side effects are mild and temporary, like redness, swelling, bruising, or tenderness. Rare but serious risks include allergic reactions, vascular occlusion, granuloma formation, or nerve damage. Choosing an experienced practitioner is key to minimizing risks.
Juvelook is not recommended for those with:
- Allergies to its components
- Pregnancy or breastfeeding
- Active skin infections or inflammation
- Certain autoimmune or bleeding disorders
- A history of skin cancer in the treatment area
- Recent cosmetic procedures in the same area
Expected Longevity of Results
Results from Juvelook Volume Filler typically last 12–18 months, sometimes up to two years, thanks to ongoing collagen production.
Juvelook Volume Filler vs. Other Injectable Treatments
Juvelook stands out among injectables:
- Traditional HA Fillers (like Juvederm): Offer immediate volume but effects fade in 6–18 months and don’t stimulate collagen.
- Sculptra: Stimulates collagen for long-term results but doesn’t provide immediate volume and requires post-treatment massage.
- Botox: Relaxes muscles to reduce dynamic wrinkles but doesn’t improve skin quality or stimulate collagen.
Juvelook’s hybrid formula delivers both instant and long-term benefits, without the need for post-injection massage.
Best Clinics in Korea for Lip Wrinkles
Listed below are the best clinics in Korea for lip wrinkles:
| Clinic Name | Key Features | Special Techniques |
|---|---|---|
| Hev Clinic | Dermatologist-led precision with a broad, evidence-based toolkit designed for natural-looking rejuvenation around the mouth. Led by board-certified dermatologists who actively participate in domestic and international academic societies, translating up-to-date techniques into safer, more personalized treatment plans built on precise skin analysis and expert consultation. Lip wrinkles can stem from repetitive muscle movement, volume loss, dehydration, and surface texture changes, so Hev can tailor care using targeted options such as Botox (including Skin Botox/Micro-Botox for fine lines without a frozen look), hyaluronic acid fillers to restore subtle lip support, collagen-stimulating Sculptra for longer-term firmness, and skin boosters like Rejuran, Juvelook, and Profhilo to improve hydration and crepiness. For texture and etched lines, resurfacing and regenerative approaches such as Fraxel or CO2 laser, microneedling or RF microneedling, PRP, and even stem cell therapy and hyperbaric oxygen therapy can be incorporated when appropriate, while energy-based lifting devices like Ultherapy, Thermage, and InMode help support surrounding laxity that can worsen perioral aging. Importantly, every procedure is performed responsibly by the same attending dermatologist from consultation through completion, ensuring consistency, safety, and trust—an approach that aligns with Hev’s focus on skin health, rejuvenation, and refined, natural results. | Botox (including Skin Botox/Micro-Botox for fine lines without a frozen look); hyaluronic acid fillers to restore subtle lip support; Sculptra; Rejuran; Juvelook; Profhilo; Fraxel; CO2 laser; microneedling; RF microneedling; PRP; stem cell therapy; hyperbaric oxygen therapy; Ultherapy; Thermage; InMode; same dermatologist from consultation through completion; emphasis on safety, consistency, and natural results. |
| Secret Clinic | Secret Clinic in Seongnam provides personalized, advanced aesthetic care for patients concerned about lip wrinkles, with treatment plans tailored through expert consultation. The clinic focuses on improving overall skin firmness and texture—key factors in softening fine lines around the mouth—by selecting procedures that match each person’s skin condition, wrinkle depth, and aging patterns. | Face InMode RF; Shrunk Universe ultrasound to support collagen and improve laxity; injectables like filler and Botox to smooth lines and rebalance perioral movement; regenerative approaches such as Rejuran, Juvelook, and Exosome Therapy can also be used to enhance hydration, elasticity, and skin quality for more naturally refreshed results, with complementary medical skincare (skin barrier, exfoliation/sebum, and elasticity care) available to optimize and maintain outcomes. |
| Beauty blossom Clinic | Beauty blossom Clinic in Hongdae is a trusted destination for non-surgical and minimally invasive aesthetic care, combining advanced technology with an experienced medical team to help clients look and feel their best. For lip wrinkles in particular, the clinic stands out for its ability to customize treatments that smooth fine lines around the mouth, restore hydration and elasticity, and improve overall skin clarity—while prioritizing natural-looking results and minimal downtime. | Comprehensive, non-surgical approach to lip wrinkles: addresses both dynamic lines (from muscle movement) and static lines (from collagen loss and dryness) using complementary treatments. Expert injectable options for perioral lines: Botox to soften wrinkle-forming muscle activity around the lips for a smoother look; dermal fillers to restore lost volume and soften deeper lines for immediate improvement; skin boosters (hyaluronic acid micro-injections) to enhance hydration, elasticity, and radiance. Advanced laser treatments to refine texture and tone: IPL and laser toning help improve photoaging, pigmentation, and dullness that can make lip wrinkles appear more prominent. Collagen-stimulating tightening solutions: Ultherapy (HIFU) and thread lifting. Strong skin-quality foundation to support results: Hydrafacial, Aqua Peel, and other skin treatments. Minimally invasive focus with minimal downtime. |
Hev Clinic
Hev Dermatology Clinic in Sinsa is widely regarded as a top choice for treating lip wrinkles in Korea because it combines dermatologist-led precision with a broad, evidence-based toolkit designed for natural-looking rejuvenation around the mouth. The clinic is led by board-certified dermatologists who actively participate in domestic and international academic societies, translating up-to-date techniques into safer, more personalized treatment plans built on precise skin analysis and expert consultation. Lip wrinkles can stem from repetitive muscle movement, volume loss, dehydration, and surface texture changes, so Hev can tailor care using targeted options such as Botox (including Skin Botox/Micro-Botox for fine lines without a frozen look), hyaluronic acid fillers to restore subtle lip support, collagen-stimulating Sculptra for longer-term firmness, and skin boosters like Rejuran, Juvelook, and Profhilo to improve hydration and crepiness. For texture and etched lines, resurfacing and regenerative approaches such as Fraxel or CO2 laser, microneedling or RF microneedling, PRP, and even stem cell therapy and hyperbaric oxygen therapy can be incorporated when appropriate, while energy-based lifting devices like Ultherapy, Thermage, and InMode help support surrounding laxity that can worsen perioral aging. Importantly, every procedure is performed responsibly by the same attending dermatologist from consultation through completion, ensuring consistency, safety, and trust—an approach that aligns with Hev’s focus on skin health, rejuvenation, and refined, natural results.
You can check out their website here: Hev Clinic Website
Secret Clinic
Secret Clinic in Seongnam provides personalized, advanced aesthetic care for patients concerned about lip wrinkles, with treatment plans tailored through expert consultation. The clinic focuses on improving overall skin firmness and texture—key factors in softening fine lines around the mouth—by selecting procedures that match each person’s skin condition, wrinkle depth, and aging patterns.
Options that may be incorporated into a lip-wrinkle plan include lifting and tightening technologies such as Face InMode radiofrequency and Shrunk Universe ultrasound to support collagen and improve laxity, along with injectables like filler and Botox to smooth lines and rebalance perioral movement. Regenerative approaches such as Rejuran, Juvelook, and Exosome Therapy can also be used to enhance hydration, elasticity, and skin quality for more naturally refreshed results, with complementary medical skincare (skin barrier, exfoliation/sebum, and elasticity care) available to optimize and maintain outcomes.
Find more about this clinic here: Secret Clinic Website
Beauty blossom Clinic
Beauty Blossom Clinic in Hongdae is a trusted destination for non-surgical and minimally invasive aesthetic care, combining advanced technology with an experienced medical team to help clients look and feel their best. For lip wrinkles in particular, the clinic stands out for its ability to customize treatments that smooth fine lines around the mouth, restore hydration and elasticity, and improve overall skin clarity—while prioritizing natural-looking results and minimal downtime.
- Comprehensive, non-surgical approach to lip wrinkles: addresses both dynamic lines (from muscle movement) and static lines (from collagen loss and dryness) using complementary treatments.
- Expert injectable options for perioral lines:
- Botox to soften wrinkle-forming muscle activity around the lips for a smoother look.
- Dermal fillers to restore lost volume and soften deeper lines for immediate improvement.
- Skin boosters (hyaluronic acid micro-injections) to enhance hydration, elasticity, and radiance—key for crepey lip lines.
- Advanced laser treatments to refine texture and tone: options such as IPL and laser toning help improve photoaging, pigmentation, and dullness that can make lip wrinkles appear more prominent.
- Collagen-stimulating tightening solutions: Ultherapy (HIFU) and thread lifting support firmer, tighter skin and help prevent worsening of fine lines over time.
- Strong skin-quality foundation to support results: Hydrafacial, Aqua Peel, and other skin treatments help maintain a healthy, hydrated complexion that complements anti-wrinkle procedures.
- Minimally invasive focus with minimal downtime: ideal for patients seeking noticeable improvement without surgery.
Find more about this clinic here: Beauty blossom Clinic Website
The Juvelook Volume Filler Procedure in South Korea: A Step-by-Step Guide
Initial Consultation and Personalized Treatment Plan
Your journey starts with a detailed consultation. The doctor assesses your needs, discusses your goals, and explains the procedure, risks, costs, and aftercare. A personalized plan is created, specifying the amount of Juvelook Volume Filler and injection sites.
Pre-Procedure Preparation
Before the procedure, the area is cleansed and numbing cream is applied for 20–30 minutes. You may be advised to stop certain medications, avoid alcohol, and limit sun exposure to reduce risks.
The Injection Process

Once numb, the clinician injects Juvelook Volume Filler using fine needles or cannulas. For lip wrinkles, small amounts are injected into each line and gently massaged for even distribution. The process takes 15–60 minutes, depending on the area.
Immediate Post-Procedure Care
After treatment, you might notice redness, swelling, or tenderness—these usually fade in a few days. Cold compresses can help. Thanks to Juvelook’s formulation, you don’t need to massage the area post-treatment. Avoid touching the area for 24 hours, and you can usually apply makeup the next day.
Long-Term Aftercare and Follow-up Sessions
Avoid strenuous activity and sun exposure for a few days. Don’t drink alcohol or smoke for about four weeks to support healing. Most people need 2–3 sessions, spaced a month apart, with maintenance every 6–18 months.
Cost Analysis: Juvelook Volume Filler for Medical Tourists
South Korea is a top destination for cosmetic procedures, offering advanced care at competitive prices.
Average Costs of Juvelook Volume Filler in South Korea
Prices vary by clinic, practitioner, and treatment extent. Juvelook Volume Filler typically costs $345–$1,033 USD per session, though some sources list $150–$300 or $300–$500. Factors like clinic location, practitioner reputation, and product concentration (50mg vs. 200mg) affect pricing. A deposit is often required to book.
Comparative Costs: South Korea vs. Other Countries
Juvelook isn’t FDA-approved in the US, so Americans must travel abroad for treatment. Here’s a cost comparison:
| Country/Region | Estimated Cost Range (USD) per Vial/Session | Notes |
|---|---|---|
| South Korea | $150 - $1,033 | Varies by clinic and product concentration. |
| USA | $500 - $1,000 | Not FDA approved; may refer to similar treatments. |
| Europe | €315 (approx. $340) | Per 50mg vial. |
| UK | £129.99 - £590 ($165 - $750) | Varies by clinic and area. |
| Australia | $200 - $990 | Varies by clinic/session. |
| Canada | $200 - $1,000+ | Varies by clinic/area. |
| Thailand | $327 - $550 | For Juvelook Skin Booster. |
The Medical Tourism Advantage: Cost Savings and Value
Medical tourists in South Korea can save 70–80% compared to US prices. Beyond savings, patients access advanced technology, comprehensive packages, and the unique experience of Korean beauty culture.
Additional Expenses for Medical Tourists
Non-medical costs to consider:
| Category | Estimated Cost Range (USD) | Notes |
|---|---|---|
| Flights (Round-trip) | $200 - $1,500 | Depends on origin and season. |
| Accommodation | $20 - $500/night | From hostels to luxury hotels. |
| Local Transportation | $30 - $100 | Affordable public transit. |
| Meals | $1 - $50/meal | Wide range of options. |
| Travel Insurance | $50 - $150 | For comprehensive coverage. |
| Sightseeing/Shopping | Varies | Based on personal preference. |
Eligibility for Medical Tourism Tax Refunds in South Korea
Foreign tourists may qualify for a 10% VAT refund on cosmetic procedures if treated at a registered clinic and staying less than six months. Always confirm your clinic’s registration to ensure eligibility.
Patient Experiences and Expected Outcomes for Lip Wrinkles
How Juvelook Volume Filler Addresses Lip Wrinkles
Juvelook Volume Filler’s HA provides instant hydration and plumping, while PDLLA stimulates collagen for long-term improvement. It smooths vertical lines, adds subtle volume, defines the lip border, and can correct minor asymmetries—all with a natural look.
Timeline of Visible Results and Gradual Enhancement
- Immediately: Noticeable plumping and hydration.
- 2–4 Weeks: Collagen production begins, improving firmness and texture.
- 3–6 Months: Peak results—more volume, smaller pores, brighter skin.
Results develop gradually, and multiple sessions are usually needed. This slow improvement contrasts with the quick but short-lived effects of traditional HA fillers.
General Patient Satisfaction and Outcomes for Fine Lines and Overall Skin Quality
While specific testimonials for lip wrinkles are limited, Juvelook is well-regarded for improving fine lines, skin firmness, and radiance. Patients often describe results as natural and rejuvenating.
Important Considerations and Realistic Expectations for Patients
- Multiple Sessions: Expect 2–3 treatments, spaced a month apart.
- Gradual Results: Full benefits take several months.
- Individual Variation: Results depend on skin type, lifestyle, and wrinkle severity.
Though direct evidence for lip wrinkles is limited, Juvelook’s general effectiveness for fine lines supports its use in this area. Discuss your goals and review before/after photos with your practitioner.
Conclusion: Making an Informed Decision for Your Skin Health
Lip wrinkles, or perioral rhytides, are a natural part of aging but can be worsened by lifestyle and environmental factors. Juvelook Volume Filler offers a unique dual-action solution, combining immediate hydration with long-term collagen stimulation for results that can last up to two years. South Korea is a leading destination for this treatment, offering advanced care and significant cost savings. For best results, consult with an experienced practitioner and approach treatment with realistic expectations about the gradual, multi-session process.














